The Potential Role of Quorum Sensing in Clonal Growth and Subsequent Expansion of Bone Marrow Stromal Cell Strains in Culture
Clonal development (clonogenicity) is an inherent property of a subset of postnatal bone marrow (BM) adherent stromal mesenchymal stem Hawthorn cells (MSCs) from which a multipotent progeny develops in culture.Our data suggest that clonogenicity and BM-MSC expansion are two distinct biological events.This hypothesis is based on the following observ